| Primary Identifier | MGI:3589260 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Peg3 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A beta-geo cassette was inserted into exon 5. Northern blot of embryos with the paternally inherited allele failed to detect wild-type transcript, however, appropriate beta-gal expression was demonstrated in the brain, pituitary and adrenal medulla of adults. Extended exposure of blots revealed a weak signal corresponding to an aberrant alternatively spliced transcript involving exon 4, 49 nucleotides from beta-geo and exon 6. Mutants with the maternally inherited allele failed to detect beta-gal activity as expected. |
