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Allele : Bace1<tm1Psa> beta-site APP cleaving enzyme 1; targeted mutation 1, Paul Saftig

Primary Identifier  MGI:3603141 Allele Type  Targeted
Attribute String  Null/knockout Gene  Bace1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin expression cassette was inserted into the first coding exon at codon 49, resulting in a premature translational stop codon. Western blot confirmed the absence of protein in mutants.
  • mutations:
  • Insertion
  • synonyms:
  • BACE1I,
  • BACE1I,
  • bace1<->,
  • bace1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

19 Publication categories

Trail: Allele