|  Help  |  About  |  Contact Us

Allele : Casp12<tm1Dgen> caspase 12; targeted mutation 1, Deltagen

Primary Identifier  MGI:3604507 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Casp12
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
Project Collection  Deltagen
molecularNote  A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RNA transcripts are detectable in: brain, cerebellum, brainstem, spinal cord, eye, Harderian gland, heart, lung, liver, pancreas, kidney, spleen, thymus, lymph nodes, bone marrow, skin, gallbladder, urinary bladder, pituitary gland, adrenal gland, salivary gland, skeletal muscle, tongue, stomach, small intestine, large intestine, cecum, testis, epididymis, seminal vesicle, coagulating gland, prostate gland, ovary, uterus and white fat. LacZ (beta-galactosidase) expression is detectable in brain, spinal cord, sciatic nerve, Harderian glands, spleen, lymph nodes, aorta, heart, lung, pancreas, kidney, urinary bladder, trachea, larynx, thyroid gland, parathyroid gland, adrenal glands, salivary glands, tongue, male and female reproductive systems. In many tissues, lacZ expression is detectable in blood vessels and ganglia.
  • mutations:
  • Disruption caused by insertion of vector
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele