| Primary Identifier | MGI:3603521 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Mchr1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A sequence from exon 2 extending from the third to the seventh transmembrane segment was replaced with a floxed PGK-neo cassette. The receptor-binding pocket was deleted as well as the Asp at amino acid position 123, which is essential for ligand-receptor interaction. Deletion was confirmed by RT-PCR and Northern blot. |
