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Allele : Tg(Prnp-MAPT)25Hlmc transgene insertion 25, Mike Hutton

Primary Identifier  MGI:3604150 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Prnp-MAPT)25Hlmc
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
description  Microinjected into fertilized mouse C57BL/DBA2/SW eggs.
molecularNote  The mouse prion protein promoter was used to drive expression of human microtubule-associated protein tau cDNA with exon 10, but lacking exons 2 and 3. These exons encode four-repeat tau without amino-terminal inserts. Hemizygous mice expressed the transgene at levels roughly equivalent to that of endogenous tau.
  • mutations:
  • Insertion
  • synonyms:
  • JN25,
  • JN25
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele