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Allele : Rr148<tm1Fwa> regulatory region 148; targeted mutation 1, Frederick W Alt

Primary Identifier  MGI:3604299 Allele Type  Targeted
Attribute String  Modified regulatory region, Null/knockout Gene  Rr148
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene cassette was inserted into the locus to replace the core Emu enhancer, located between the Igh J and Cmu gene segments. These mice had a complete block of V(D)JH recombination.
  • mutations:
  • Disruption caused by insertion of vector
  • synonyms:
  • Igh<tm1Fwa>,
  • cEmu<N>,
  • Igh<tm1Fwa>,
  • cEmu<N>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele