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Allele : Efemp2<tm1Dgen> epidermal growth factor-containing fibulin-like extracellular matrix protein 2; targeted mutation 1, Deltagen

Primary Identifier  MGI:3604551 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Efemp2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
Project Collection  Deltagen
molecularNote  A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a gene transcript in all tissues tested, strong beta-galactosidase expression from this allele is detectable in brain, spinal cord, eyes, Harderian glands, thymus, spleen, lymph nodes, aorta, heart, lung, liver, gallbladder, pancreas, kidney, urinary bladder, trachea, larynx, esophagus, thyroid gland, pituitary gland, adrenal glands, salivary glands, tongue, skeletal muscle, skin, male and female reproductive systems. In many tissues lacZ is expressed in smooth muscle cells.
  • mutations:
  • Insertion
  • synonyms:
  • Fbln4<->,
  • Fbln4<->,
  • fibulin-4<->,
  • fibulin-4<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele