|  Help  |  About  |  Contact Us

Allele : Gpr151<tm1Dgen> G protein-coupled receptor 151; targeted mutation 1, Deltagen

Primary Identifier  MGI:3604578 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Gpr151
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
Project Collection  Deltagen
molecularNote  A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in the lymph nodes, moderate levels in cerebellum, olfactory bulb, spinal cord, Harderian glands, lung, liver, pancreas, skin, urinary bladder, pituitary gland, adrenal gland, tongue, stomach, small intestine, epididymis, coagulating gland, prostate gland, ovary and uterus and low levels in whole brain, cortex, subcortical region, brainstem, eye, heart, kidney, spleen, thymus, bone marrow, gallbladder, salivary gland, large intestine, cecum, testis, seminal vesicle and white fat. Beta-galactosidase expression from this allele is detectable only in brain. In the whole mount brain, moderate staining was observed in the thalamus and cerebellum with weak staining in the brainstem. On coronal sections, faint expression was detected in a few cells in the Purkinje cell layer of the cerebellum.
  • mutations:
  • Disruption caused by insertion of vector
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele