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Allele : Cbfa2t2<tm1Swh> CBFA2/RUNX1 translocation partner 2; targeted mutation 1, Scott W Hiebert

Primary Identifier  MGI:3607923 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cbfa2t2
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted into exon 7, which is within the first conserved domain that is found in all family members. RT-PCR analysis confirmed that a transcript lacking exon 7 was expressed from this allele, but both immunoblot analysis, and immunoprecipitation, followed by immunoblot analysis with purified antibodies directed to the N terminus of indicated that neither a full-length nor a truncated Mtgr1 protein was produced at detectable levels.
  • mutations:
  • Insertion
  • synonyms:
  • Mtgr1<->,
  • Mtgr1<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele