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Allele : Ret<tm5(RET)Vpa> ret proto-oncogene; targeted mutation 5, Vassilis Pachnis

Primary Identifier  MGI:3607931 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Ret
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A cDNA fragment encoding the intracellular portion of the human RET9 isoform was fused in-frame with mouse exon 11 immediately downstream of the transmembrane domain-coding region. The inserted cDNA contained substitutions changing the amino acids M and S at the start of the Ret51 specific sequence to R and I, and was followed by a floxed PGK-neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Ret9<51-RI>,
  • Ret9<51-RI>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele