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Allele : Casp8<tm1Syon> caspase 8; targeted mutation 1, S Yonehara
Primary Identifier  MGI:3609638 Allele Type  Targeted
Attribute String  Null/knockout Gene  Casp8
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A stop codon, SV40 polyA sequence and a pgk-neo cassette was inserted into exon 7 via homologous recombination. RT-PCR of mutants detected a truncated transcript. Immunoblot analysis detected a peptide at 25 kDa corresponding to the DED domains of the gene.
  • mutations:
  • Insertion
  • synonyms:
  • caspase-8<DED>,
  • caspase-8<DED>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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