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Allele : Ptgis<tm1Tada> prostaglandin I2 (prostacyclin) synthase; targeted mutation 1, Tadashi Tanabe

Primary Identifier  MGI:3610729 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptgis
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was used to replace part of exon 7 and all of exons 8 and 9 with a neomycin resistance gene. RNA blot and immunoblot of mutants failed to detect transcript and protein, respectively, in mutant lungs.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Ptgis<->,
  • PGIS-null,
  • Ptgis<->,
  • PGIS-null,
  • PGIS<->,
  • PGIS<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele