Primary Identifier | MGI:3613513 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Apoe |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A portion of the endogenous locus, spanning from within exon 2 through most of exon 4, was replaced by the human cDNA encoding APOE isoform 2. Mouse protein was not detected in Western blot of mutants. Human protein was shown to be robustly expressed. |