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Allele : Tg(MMTV-PyVT*Y250F)250-2Mul transgene insertion 250-2, William Muller

Primary Identifier  MGI:3614339 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(MMTV-PyVT*Y250F)250-2Mul
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
description  Total of 8 lines were produced, of which two lines 250-2 and 250-5 had similar phenotype. These mice were used to study metastatic disease and they had similar phenotype.
molecularNote  This transgene expresses mutant plyomavirus middle T antigen with Y to F mutation at position 250 under the control of the mouse mammary tumor virus LTR. Expression of this transgene was detected at high levels in male and female mammary glands. Other expression sites include salivary gland, seminal vesicles, ovaries, and lung.
  • mutations:
  • Insertion
  • synonyms:
  • MMTV/MT-Y250F,
  • MMTV/MT-Y250F
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele