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Allele : Ret<tm5(RET)Jmi> ret proto-oncogene; targeted mutation 5, Jeffrey Milbrandt

Primary Identifier  MGI:3614430 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence, Null/knockout Gene  Ret
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert human isoform RET51 containing a replacement of residues 1063-1072 with residues 1063-1072 of human isoform RET9. This resulted in an allele similar to Rettm2(RET)Jmi, but has the C-terminus of RET51 containing a Y1096 not present in RET9. Endogenous transcript was not detected in mutants; however, transcript from the inserted human RET9 sequence was detected.
  • mutations:
  • Insertion
  • synonyms:
  • RET9(51C),
  • RET9(51C)
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele