Primary Identifier | MGI:3614822 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Pmp22 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Velocigene technology was used to insert a cassette containing a lacZ-stop-PGK-noe-stop cassette immediately downstream of the ATG in exon 2, subsequently replacing the rest of exon 2 and all of exon 3. Western blot did not detect protein in mutant sciatic nerve lysates. Beta-gal expression was detected widely in the E15 mouse embryo. |