| Primary Identifier | MGI:3617327 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Notch2 |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A betagalactosidase-neo cassette replaced the exon 3 splice donor site and most of intron 3. The lacZ was inserted in frame with amino acid 118 in the third EGF repeat of the extracellular domain. RT-PCR detected two small transcripts expressed at low levels, resulting from alternative splicing around the inserted sequence. |