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Allele : Notch2<tm2Grid> notch 2; targeted mutation 2, Tom Gridley

Primary Identifier  MGI:3617327 Allele Type  Targeted
Attribute String  Null/knockout Gene  Notch2
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A betagalactosidase-neo cassette replaced the exon 3 splice donor site and most of intron 3. The lacZ was inserted in frame with amino acid 118 in the third EGF repeat of the extracellular domain. RT-PCR detected two small transcripts expressed at low levels, resulting from alternative splicing around the inserted sequence.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Notch2<del2>,
  • Notch2<del2>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele