| Primary Identifier | MGI:3617404 | Allele Type | Targeted |
| Gene | Rr70 | Transmission | Germline |
| Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exons 3-9 of the Hprt minigene, a loxP site and a puromycin resistance gene cassette were inserted 13 kb upstream of exon 1. The mutation also included a 6 kb genomic duplication of the 7-13 kb upstream sequence. Maternal inheritance of this allele leads to Snrpn imprinting defects, leaving the maternal Snrpn allele unmethylated. |
