| Primary Identifier | MGI:3620555 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(GFAP-CDK4)2Gtm |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| description | This is one of three lines reported; the others are lines 8 and 27. No distinction is made among them in the primary reference. |
| molecularNote | The transgene comprises a 2.2 kb 5' flanking fragment containing the promoter and upstream regulatory elements of the human glial fibrillary acidic protein gene joined to a 912 bp DNA fragment encoding human CDK4 followed by a 0.5 kb fragment containing an intron and the polyadenylation signal from the mouse protamine 1 gene. RT-PCR demonstrated expression of mRNA and western blot analysis of protein in astrocytes. |
