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Allele : Ikbkg<tm1Mka> inhibitor of kappaB kinase gamma; targeted mutation 1, Michael Karin

Primary Identifier  MGI:3620102 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ikbkg
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  This allele was created by using one of two vectors. The first vector was designed to insert a beta-lactamase cassette, a stop codon and a neomycin resistance gene in frame with the first ten codons. The second vector was designed to remove most of the coding sequence in the first exon and replace it with a beta-lactamase and neomycin resistance cassette. Western blot failed to detect protein in mutant ES cells.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • NEMO<->,
  • NEMO<->,
  • Ikkgamma<->,
  • Ikkgamma<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele