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Allele : Blm<tm1Khor> Bloom syndrome, RecQ like helicase; targeted mutation 1, Kyoji Horie

Primary Identifier  MGI:3620977 Allele Type  Targeted
Attribute String  Hypomorph Gene  Blm
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing a tetracycline-controlled transactivator (tTA), and a tetracycline responsive element (TRE) was inserted upstream of the translation start site in exon 2. Blm expression in mutants was present in the absence of dox. Upon administration of dox, expression was reduced, however, leaky expression was found in all tissues examined.
  • mutations:
  • Insertion
  • synonyms:
  • Blm<tet>,
  • Blm<tetN>,
  • Blm<tet>,
  • Blm<tetN>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

7 Publication categories

Trail: Allele