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Allele : Prnp<tm1Canc> prion protein; targeted mutation 1, Enrico Cancellotti

Primary Identifier  MGI:3619122 Allele Type  Targeted
Gene  Prnp Transmission  Germline
Strain of Origin  129P2/OlaHsd-Hprt1<b-m3> Is Recombinase  false
Is Wild Type  false
molecularNote  Homologous recombination was used to insert a N180T mutation into exon 3 in order to eliminate the first glycosylation site. Northern blot demonstrated presence of the mutation does not interfere with transcription.
  • mutations:
  • Insertion
  • synonyms:
  • G1,
  • G1
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele