| Primary Identifier | MGI:3621174 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Hprt1 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | The rat phosphoenolpyruvate carboxykinase 1, cytosolic promoter was used to drive expression of cre recombinase in the renal proximal tubule. The promoter was mutated in such a way that expression in the liver was reduced by 60% and increased in the kidney by 10-fold in mutant mice. The construct was inserted into ES cells lacking Hprt. |
