| Primary Identifier | MGI:3621049 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Emd |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| description | Mild clinical phenotypic expression similar to Emery-Dreifuss Muscular Dystrophy (OMIM ID: 310300) but symptoms are mild and no dystrophic changes are seen. |
| molecularNote | A vector was designed to delete sequence encoding the C-terminal 84 amino acids, including the transmembrane domain of the locus by replacing 702 bp with a bovine growth hormone polyA sequence and neo gene. Immunoblot failed to detect wild-type protein in mutants. |
