Primary Identifier | MGI:3622199 | Allele Type | QTL |
Gene | Pgis1 | Inheritance Mode | Recessive |
Strain of Origin | DBA/2 | Is Recombinase | false |
Is Wild Type | false |
description | F2 animals homozygous for DBA/2-derived alleles at Pgis1 and homozygous for BALB/c-derived alleles at Pgis2 exhibit the highest spondylitis incidence and severity. |
molecularNote | This allele confers susceptibility to proteoglycan-induced spondylitis compared to BALB/c. |