Primary Identifier | MGI:3623118 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Hcls1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 10 was disrupted by the insertion of a lacZ-neo cassette. A truncated protein comprised of residues 1-237 could potentially be produced, but would lack the acidic and amphipathic alpha-helix structure and the SH3 region. Protein was not detected in mutants. |