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Allele : Tnks2<tm1.1Susm> tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; targeted mutation 1.1, Susan Smith
Primary Identifier  MGI:3621820 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tnks2
Transmission  Germline Strain of Origin  129/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace exons 25-27, encoding the PARP domain, with a neomycin resistance cassette. The vector was designed using the exon nomenclature in J:71663. The neo was removed via cre mediated recombination. This allele was expected to produce a null, however, truncated protein was detected.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Tnks<Pddeltaneodelta>,
  • Tnks<Pddeltaneodelta>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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4 Publication categories

Trail: Allele




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