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Allele : Tg(HBB-GH1)420King transgene insertion 420, Donna King

Primary Identifier  MGI:3625833 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(HBB-GH1)420King
Strain of Origin  (C57BL/6J x SJL/J)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The human genomic growth hormone gene, from its transcription initiation site through the 3' untranslated region, was placed under control of the sheep hemoglobin betac promoter joined at its 5' end to a 1.9-kb fragment containing the 5' HS-2 element of the human hemoglobin beta locus control region. Radiolabeled human growth hormone antisense RNA detects transcripts in liver and heart (in the latter presumably from pooled blood) of whole-embryo sections and in bone marrow of sectioned adult tibiae.
  • mutations:
  • Insertion
  • synonyms:
  • HS-2 + beta-c hGH,
  • Tg420,
  • HS-2 + beta-c hGH,
  • Tg420
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele