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Allele : Adam11<tm1Sag> a disintegrin and metallopeptidase domain 11; targeted mutation 1, Koji Sagane

Primary Identifier  MGI:3625523 Allele Type  Targeted
Attribute String  Null/knockout Gene  Adam11
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace exon 6 and part of exons 5 and 7 with a neomycin resistance gene. A termination was introduced into exon 5 in the pro-protein domain as a result, and any protein synthesized from this allele would be truncated and non-functional. Absence of protein in mutant cerebellum was confirmed by Western blot analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele