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Allele : Tg(ACTA1-IGF1)1Rjs transgene insertion 1, Robert J Schwartz
Primary Identifier  MGI:3630335 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(ACTA1-IGF1)1Rjs
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  The proximal promoter region, together with the first intron and 1.8 kilobases of 3'-noncoding flanking sequence of the avian skeletal alpha-actin gene directs the expression of human insulin-like growth factor 1 (IGF1). Transgenic mice harbor a single copy of the transgene that is expressed in striated muscle and is more abundant in skeletal muscle than in the heart. IGF1 concentration is elevated 47-fold in skeletal muscle.
  • mutations:
  • Insertion
  • synonyms:
  • SK733 IGF-1 3'-SK,
  • SK733 IGF-1 3'-SK,
  • SIS2,
  • SIS2
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele




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