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Allele : Tg(Ckm-Prkaa2*K45R)1Mbb transgene insertion 1, Morris J Birnbaum

Primary Identifier  MGI:3639284 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Ckm-Prkaa2*K45R)1Mbb
Strain of Origin  (C57BL/6J x SJL/J)F1/J Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene contains the full length cDNA of rat Prkaa2 with the lysine at residue 45 (residue critical for ATP binding and hydrolysis) changed to arginine and tagged at the 5'end with a myc epitope under the control of the muscle creatine kinase promoter. Expression of endogenous Prkaa2 is completely undetectable and transgene expression occurs in skeletal and cardiac muscle.
  • mutations:
  • Insertion
  • synonyms:
  • Tg-KD1,
  • alpha2 AMPK KD,
  • alpha2 AMPK KD,
  • Tg-KD1
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

49 Publication categories

Trail: Allele