Primary Identifier | MGI:3639305 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Malt1 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to replace exon 8 of the locus. Exon 8 encodes the N-terminal region of the paracaspase domain. RT-PCR confirmed loss of transcript in mutant thymocytes. Western blot failed to detect protein from mutant spleens. |