| Primary Identifier | MGI:3653425 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Foxn1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | This allele was created to be a conditional mutant whereas insertion of the targeting vector interrupts expression of the locus and expression of cre recombinase restores the function of the endogenous gene. The vector contains a cassette containing 2 copies of a 605 bp sequence, each containing a splice acceptor and polyA signal, and a hygromycin resistance gene. The cassette was flanked by loxP sites and inserted into intron 6 along with a 555 bp deletion of intronic sequence to facilitate the detection of cre-mediated remoal of the SA2-hyg cassette. |
