| Primary Identifier | MGI:3653745 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(CMV-IL3,CSF2,KITLG)1Eav |
| Strain of Origin | (C57BL/6 x C3H/HeN)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | cDNAs encoding human interleukin 3, colony stimulating factor 2 (granulocyte-macrophage) and kit ligand were independently ligated into expression cassettes in which the cDNA resides downstream of the cytomegalovirus (CMV) promoter/enhancer sequence and is followed by human growth factor intronic and polyadenylation sequences. A transgenic mouse that was shown by ELISA to have serum levels of all three growth factors at ng/ml levels was used to establish a line with the same phenotype. |
