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Allele : Tg(KRT14-Vegfa)3Dtm transgene insertion 3, Michael Detmar

Primary Identifier  MGI:3655101 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(KRT14-Vegfa)3Dtm
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  cDNA encoding murine VEGF164 was inserted behind a keratin-14 expression cassette. The purified construct was injected into fertilized FVB/N embryos that were implanted into pseudo-pregnant C21 females. In situ analysis of transgenic mice confired selectively increased VEGF expression in the basal keratinocyte layer of the epidermis and in outer sheath keratinocytes of hair follicles.
  • mutations:
  • Insertion
  • synonyms:
  • K14-VEGF,
  • K14/VEGF-A,
  • K14-VEGF,
  • K14/VEGF-A
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

20 Publication categories

Trail: Allele