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Allele : Il4<tm1(CD2)Irvr> interleukin 4; targeted mutation 1, Isabelle Riviere

Primary Identifier  MGI:3664115 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Il4
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert a mutant human CD2 and a neo cassette in place of exon 1. The mutant CD2 was altered such that the cytoplasmic domain and ligand binding activity were eliminated. The endogenous gene was completely disrupted but the CD2 expression was preserved.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele