| Primary Identifier | MGI:3664552 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ciita |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A single loxP site was introduced 5' to exon 2 and a loxP-flanked thymidine kinase-neomycin fusion gene was inserted 3' to exon 3. Cre-mediated deletion of the intervening sequences was accomplished by mating mutant mice to CMV-cre mice, deleting the DNA encoding the major transactivation domain. RT-PCR analysis on spleen and thymus RNA indicated that no detectable transcript is expressed from this allele. |
