| Primary Identifier | MGI:3665133 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Adora2b |
| Transmission | Germline | Strain of Origin | 129/Sv |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 1, including the initiation codon, was replaced with a reporter construct containing a lacZ gene, stop codon and poly(A) signal. RNA transcripts were quantified in various tissues using RT-PCR to confirm gene ablation. Beta-galactosidase expression is observed in the vasculature of all major organ systems tested. Some ectopic expression is also noted. |