| Primary Identifier | MGI:3665432 | Allele Type | Targeted |
| Attribute String | Modified isoform(s) | Gene | Gabbr1 |
| Transmission | Germline | Strain of Origin | BALB/c |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The start codon for the B1a isoform of Gabbr1 was converted into a stop codon to prevent translation of the B1a isoform. A putative alternative start site was also mutated and a floxed neomycin cassette was inserted in the introns between exons 2a and 3a. The neomycin cassette was removed by crossing with mice expressing Cre-recombinase under the control of the cytomegalus virus promoter. Northern blot analysis confirmed absence of the B1a isoform. |
