| Primary Identifier | MGI:3665247 | Allele Type | Spontaneous |
| Gene | Etn3 | Inheritance Mode | Dominant |
| Strain of Origin | CD-1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A novel type II early transposon (ETnIIbeta) spontaneously inserted 1.6 Kb downstream of the polyadenylation signal of Dusp9 between two repetitive sequences (SINE and LINE elements) at position ChrX: 73645160 (GRCm38/mm10). This insertion does not disrupt Dusp9, Pnck or any other gene or noncoding RNA. RT-PCR and western blot analysis confirmed increased Dusp9 transcript and protein expression, respectively, in mutant ES cells. |
