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Allele : Acta2<tm1Rjs> actin alpha 2, smooth muscle, aorta; targeted mutation 1, Robert J Schwartz

Primary Identifier  MGI:3665248 Allele Type  Targeted
Attribute String  Null/knockout Gene  Acta2
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  A pol2neobpA cassette was inserted into the locus between the promoter and the coding region to disrupt transcription. Northern blots confirmed absence of transcript in mutant aorta, intestine and uterus. Western blot confirm absence of protein in mutant aorta, intestine and uterus.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

14 Publication categories

Trail: Allele