Primary Identifier | MGI:3665252 | Allele Type | Spontaneous |
Gene | Jak3 | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This mutation corresponds to a T to A point mutation in the sequences encoding the kinase-1 domain, and thus generated a stop codon in place of a codon encoding for tyrosine 887. This mutation abrogates the expression of Jak3 protein. |