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Allele : Slc12a5<tm1Dlp> solute carrier family 12, member 5; targeted mutation 1, Eric Delpire

Primary Identifier  MGI:3686895 Allele Type  Targeted
Attribute String  Hypomorph Gene  Slc12a5
Transmission  Germline Strain of Origin  129/Sv
Is Recombinase  false Is Wild Type  false
description  ES cell line = LT-1.
molecularNote  A large portion of exon 1 was replaced with a PGK-neo cassette. Western blot analysis indicated a greater than 95% reduction in protein expression suggesting that this allele is a severe hypomorph.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • KCC2b<->,
  • KCC2b<->,
  • KCC2<->,
  • KCC2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

20 Publication categories

Trail: Allele