| Primary Identifier | MGI:3687002 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Igh |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A targeting vetor was used to replace the JH1 and JH2 elements with the D23stop joint. A floxed neo included in the vector was subsequently removed by transient transfection of cre recombinase. A second targeting vector was then used to introduce a double loxP site and frt-flanked neo into the VH81x position. Crossing these mice with cre deleter mice results in the loss of the DH elements and the insertion of a D23stop VDJ cassette. |
