| Primary Identifier | MGI:3687384 | Allele Type | Targeted |
| Attribute String | Conditional ready, Dominant negative, Inserted expressed sequence, Reporter | Gene | Pax3 |
| Transmission | Germline | Strain of Origin | 129S2/SvPas |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A sequence encoding a floxed GFP-FRT-puro cassette followed by a form of Pax3 that acts as a transcriptional repressor was targeted to the locus. The repressor sequence contains the N-terminus of the Pax3 DNA-binding domains fused to the repression domain of the Drosophila Engrailed transcriptional repressor. Cre mediated recomibination results in the loss of the floxed GFP-FRT-Puro cassette and creates a dominant negative allele. |
