Primary Identifier | MGI:3693354 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Cask |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The first coding exon of the Cask gene is flanked by loxP sites and a neomycin cassette is inserted into the intron adjacent to the floxed intron. The resulting allele is a hypermorph with Cask expression decreased by ~66%. |