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Allele : Tg(Myh6-Tnnt2)191Lnwd transgene insertion 191, Leslie A Leinwand

Primary Identifier  MGI:3692603 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-Tnnt2)191Lnwd
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  This transgene expresses a carboxy-terminal truncated mouse Tnnt2 gene under the control of a rat alpha-myosin heavy chain promoter. The truncation corresponds to a truncation described in familial hypertrophic cardiomyopathy patients in which exons 15 and 16 are missing. This line expresses less than 5% of total Tnnt2 as the mutant transgenic form but expresses slightly more transgene than line 117.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

10 Publication categories

Trail: Allele