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Allele : Gfap<tm2Mes> glial fibrillary acidic protein; targeted mutation 2, Albee Messing

Primary Identifier  MGI:3692741 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Gfap
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to insert the R236H mutation in exon 4 that is found in Alexander Disease patients. Quantitative real-time PCR showed that Gfap expression is elevated.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Gfap<tm2Hgmn>,
  • GFAP R236H,
  • Gfap<tm2Hgmn>,
  • GFAP R236H
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

22 Publication categories

Trail: Allele