Primary Identifier | MGI:3692741 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Gfap |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was designed to insert the R236H mutation in exon 4 that is found in Alexander Disease patients. Quantitative real-time PCR showed that Gfap expression is elevated. |