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Allele : Tg(Thy1-EGFP)JJrs transgene insertion J, Joshua R Sanes

Primary Identifier  MGI:3693894 Allele Type  Transgenic
Attribute String  Reporter Gene  Tg(Thy1-EGFP)JJrs
Strain of Origin  (C57BL/6J x CBA)F1 Is Recombinase  false
Is Wild Type  false
description  Transgenic mice express spectral variants of GFP at high levels in motor and sensory neurons, as well as in subsets of central neurons. Axons are brightly fluorescent all the way to the terminals. No expression is detectable in nonneural cells. Fluorescence is stable to mild aldehyde fixation. Expression is strong from a mid-gestational stage into adulthood.
molecularNote  The transgene contains a GFP gene under the direction of regulatory elements derived from the mouse Thy1 gene. Regulatory elements are composed of a 6.5 kb fragment obtained from the 5' portion of the Thy1 gene, extending from the promoter to the intron following exon 4. Exon 3 and its flanking introns are absent.
  • mutations:
  • Insertion
  • synonyms:
  • GFP-J,
  • Tg(Thy1-GFPJ)1Jrs,
  • GFP-J,
  • Tg(Thy1-GFP)JJrs,
  • Tg(Thy1-GFPJ)1Jrs,
  • Tg(Thy1-GFP)JJrs
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele