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Transgene : Tg(Prnp-App/APPswe)E1-2Dbo transgene insertion E1-2, David R Borchelt
Primary Identifier  MGI:3696469 Organism  mouse, laboratory
Chromosome  UN Mgi Type  transgene
description  PHENOTYPE: Mice express ~3-fold higher levels of the Swedish variant of human APP than normal levels of mouse App. At levels sufficient to induce plaque formation (age 24-26 months), no abnormalities in neural circuits involved in spatial or nonspatial memeory are observed. [provided by MGI curators]
  • synonyms:
  • Mo/Hu APPswe line E1-2,
  • Mo/Hu APPswe,
  • transgene insertion E1-2, David R Borchelt,
  • line E1-2,
  • E1-2 line,
  • Tg(Prnp-App/APPswe)E1-2Dbo
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